Maajo 1, 2025, Hansoh Pharmaceutical waxay ku dhawaaqday in daawada isku-darka ee B7-H4 ee kooxda iska soo saartay ee la beegsanayo antibody-drug conjugate (ADC) HS-20089 ee loogu talagalay in lagu duro ay heshay oggolaansho ah in lagu daro Daawaynta Degdegga ah ee ay u qoondaysay Maamulka Badeecadaha Caafimaadka Qaranka (NMPA) ee Shiinaha, iyadoo la soo jeediyay tilmaan loogu talagalay kansarka ugxan-sidaha ee soo noqnoqda ee platinum-ka, kansarka tuubada fallopian ama bukaanada kansarka caloosha ee aasaasiga ah.
Magacaabista waxaa taageeraya natiijooyinka daraasadda Wajiga I HS-20089-101 iyo daraasadda Wajiga II HS-20089-201. Daraasadda HS-20089-101 waa tijaabo caafimaad oo Wajiga I ah oo xarun badan leh, furan si loo qiimeeyo badbaadada, dulqaadka, farmashiyaha, iyo waxtarka HS-20089 ee loogu talagalay duritaanka bukaanada qaba burooyinka adag ee horumarsan. Daraasadda HS-20089-201 waa tijaabo caafimaad oo Wajiga II ah oo xarun badan leh, furan si loo qiimeeyo waxtarka, badbaadada, astaanta farmashiyaha, iyo difaaca jirka ee HS-20089 ee xididka bukaanada qaba kansarka ugxan-sidaha ee soo noqnoqda ama metastatic iyo kansarka endometrial.
HS-20089 waa ADC-bartilmaameed u ah B7-H4 oo leh culays topoisomerase inhibitor (TOPOi) oo loo sameeyay daaweynta kansarka ugxan-sidaha iyo burooyinka kale ee haweenka ee tijaabooyin caafimaad oo badan oo laga sameeyay Shiinaha, iyadoo marxaladda cilmi-baarista ugu sarreysa ay tahay tijaabooyin caafimaad oo wejiga III ah. B7-H4 waa glycoprotein-ka baaritaanka difaaca jirka ee transmembrane kaas oo si aad ah loogu muujiyo burooyinka adag ee badan, oo ay ku jiraan kansarka endometrial iyo kansarka ugxan-sidaha, laakiin leh muuqaal xaddidan oo ku jira unugyada caadiga ah.
Waqtigan xaadirka ah, waxaa weli jira tijaabooyin caafimaad oo badan oo ku saabsan teknoolojiyada cusub ee ka hortagga kansarka ee Shiinaha oo raadinaya bukaanno. La-tashi ku saabsan daawooyinka cusub iyo teknoolojiyada, waxaad la xiriiri kartaa Waaxda Caalamiga ah ee Isbitaalka Oncology ee Gobolka Koonfureed ee Beijing.
Lambarka Taleefanka: 4008803716
Iimayl:myimmnet@163.com
Waqtiga boostada: Maajo-09-2025